CROSSTALK AND ULTRASENSITIVITY IN PROTEIN DEGRADATION PATHWAYS.

Crosstalk and ultrasensitivity in protein degradation pathways.

Protein turnover is vital to cellular homeostasis.Many proteins are degraded efficiently only after they have been post-translationally "tagged" with a polyubiquitin chain.Ubiquitylation is a form of Post-Translational Modification (PTM): addition of a hellfire sloe gin ubiquitin to the chain is catalyzed by E3 ligases, and removal of ubiquitin is

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Social accessibility in queering code/space: Blued-based visibility and social practices of local gay people in mainland China

As a locative media, Blued articulates physical and digital space in the form of localization, giving a mediated visibility to its users who are not visible in physical space, thus making the city a 5326058hx queering code/space.This can transform social accessibility and the ways that gays come together and interact in local spaces.Taking mainland

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A review of therapeutic potentials of milk thistle (Silybum marianum L.) and its main constituent, silymarin, on cancer, and their related patents

For more than 2000 years, Silybum marianum L.(milk thistle) has been used for treating different complications such as jaundice, hepatitis, and cancers.It has also been shown that silymarin, a flavonolignan extract of the plant, demonstrates chemopreventive effects against cancers.This patent review presents and discusses recent patents concerning

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Argumentative Strategies and Stylistic Devices

The extended pragma-dialectical argumentation theory assumes that people engaged in argumentative discourse manoeuvre strategically.In argumentative reality, the strategic manoeuvring chainsaw file is often carried out according to an argumentative strategy.Language users make an effort to present their strategic manoeuvres in a specific way and th

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